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Company calls on FDA to issue permit for genetically modified mosquitoes

 

  A company with a swarm of genetically modified mosquitoes wants   the Food and Drug Administrationto grant emergency approval for   the controversial insects' use in the fight against the Zika virus.

 Oxitec changed the DNA of the Aedes aegypti mosquitoes that    spread the virus so their offspring die before adulthood, Hadyn  Parry, the British company's CEO, told the House of    Representatives' Committee on Science, Space, and Technology in Washington on Wednesday. The company deploys only male mosquitoes, which cannot bite, to halt transmission of the disease, he added.

"I don’t think time is on our side with Zika," Parry said.

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African Monkeys Caught Eating Bats For the First Time

Researchers working in Africa are the first to observe monkeys preying on bats. The unusual behavior, which may have something to do with loss of habitat, could explain how dangerous diseases such as Ebola spread among species—and eventually to humans.

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Resilient Health Systems Can Prevent and Contain Pandemics

Resilience is one of those buzzwords that every so often captures the hearts and minds of development practitioners. The importance of this particular term, though, becomes all too clear as the world faces an increasing number of humanitarian crises, including outbreaks that can turn into pandemics.

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Beyond Contact Tracing: Community-Based Early Detection for Ebola Response

Introduction: The 2014 Ebola outbreak in West Africa raised many questions about the control of infectious disease in an increasingly connected global society. Limited availability of contact information made contact tracing diffcult or impractical in combating the outbreak. 

Methods: We consider the development of multi-scale public health strategies that act on individual and community levels. We simulate policies for community-level response aimed at early screening all members of a community, as well as travel restrictions to prevent inter-community transmission. 

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Late Ebola Virus Relapse Causing Meningoencephalitis: a Case Report

thelancet.com - May 18, 2016 - DOI: http://dx.doi.org/10.1016/S0140-6736(16)30386-5

Interpretation

Our report shows that previously unanticipated, late, severe relapses of Ebola virus can occur, in this case in the CNS. This finding fundamentally redefines what is known about the natural history of Ebola virus infection. Vigilance should be maintained in the thousands of Ebola survivors for cases of relapsed infection. The potential for these cases to initiate new transmission chains is a serious public health concern.

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Casual healthcare contact with Ebola survivors poses low risk

Non-invasive contact with Ebola survivors 6 weeks after the virus has been cleared poses little risk for healthcare workers, though contact with semen, ocular humor, and cerebrospinal fluid requires Ebola-appropriate precautions, according to a study yesterday in The Lancet Infectious Diseases.

A cross-sectional cohort study evaluated 555 specimens from 112 Ebola survivors without fever seeking follow-up care at a clinic in Freetown, Sierra Leone, from Apr 2 to Jun 16, 2015. Almost one third of survivors (34, or 30%) were under the age of 16, and 50 (40%) were male.

Samples were obtained from the armpit (103 specimens), blood (93), conjunctiva (92), forehead (54), mouth (105), rectum (17), semen (1), urine (69), and vagina (21). The median time from Ebola treatment unit discharge to specimen collection was 142 days.

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WHO calls emergency meeting on yellow fever outbreak

GENEVA - The World Health Organization will hold an emergency meeting Thursday on the yellow fever outbreak that has hit hardest in Angola but risks spreading further if vaccinations are not ramped up.

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Sexual transmission involved in tail end of Ebola epidemic

Some of the final cases of Ebola in Sierra Leone were transmitted via unconventional routes, such as semen and breastmilk, according to the largest analysis to date of the tail-end of the epidemic.


An international team of researchers has produced a detailed picture of the latter stages of the outbreak in Sierra Leone, using real-time sequencing of Ebola virus genomes carried out in a temporary laboratory in the country.

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Deadly virus detected in sperm of survivors months after recovery

The deadly virus is passed on through contact with body fluids and 

The epidemic has now been declared over but researchers have monitored 450 survivors of both sexes for a year, testing tears, saliva, faeces, vaginal fluids and semen every three months thereafter.

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WHO Ebola Situation Report

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