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Medical Research: Ebola Therapy Protects Severely Ill Monkeys

nature.com

Thomas W. Geisbert

Nature 514, 41–43 (02 October 2014) doi:10.1038/nature13746 - Published online 29 August 2014

A blend of three monoclonal antibodies has completely protected monkeys against a lethal dose of Ebola virus. Unlike other post-infection therapies, the treatment works even at advanced stages of the disease. See Article p.47

http://www.nature.com/nature/journal/v514/n7520/full/nature13746.html

Reversion of advanced Ebola virus disease in nonhuman primates with ZMapp

Nature 514, 47–53 (02 October 2014) doi:10.1038/nature13777
Received 05 August 2014 - Accepted 21 August 2014 - Published online 29 August 2014

Abstract

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Ebola's shadow extends to would-be Mecca pilgrims

 

TWO ARTICLES ON EBOLA CONCERNS DURING THE HAJJ

 

Al Jazeera                              Oct 5, 2014

Millions of pilgrims from all corners of the world traveled to Saudi Arabia for the start of the hajj in the past week, but some West African Muslims will not be able to take part in the sacred journey this year because of public health fears surrounding the Ebola outbreak.

Saudi Arabia issued a travel ban on citizens of Liberia, Guinea and Sierra Leone as what it called a “precautionary measure,” saying the risk of Ebola infection is too high for travelers from those countries to be allowed entry now.

The Ebola-stricken countries each have sizable Muslim populations... Saudi authorities have turned down about 7,000 requests for hajj visas from the three countries because of Ebola concerns, according to the United Nations.

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Why We Won't Have An Ebola Cure Or Vaccine For Years

UPDATE with comments from interviw with CDC Director Tom Frieden.   Scroll below.

 

huffingtonpost.com - October 2nd, 2014 - Jeffery Young

The world has known about Ebola for almost 40 years, yet there's no cure or vaccine on the market.

That could change amid worldwide attention to the ongoing outbreak of the virus in West Africa, which has claimed more than 3,000 lives already, and the first diagnosis of a patient with the disease in the United States. But not for a few more years -- at least.

(VIEW COMPLETE ARTICLE)

 

Update: Comments by CDC Director on Sunday TV interview

http://www.nbcnews.com/storyline/ebola-virus-outbreak/cdc-director-tom-frieden-ebola-drug-pipeline-will-be-slow-n218666


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Are Hospitals Prepared for Ebola?

cnn.com - October 1, 2014

CNN's Jake Tapper speaks to Gavin Macgregor-Skinner and Jeffery Stern. With the first Ebola diagnosis in the U.S., is the country prepared to handle a potential outbreak?

http://thelead.blogs.cnn.com/2014/10/01/only-four-u-s-hospitals-prepared-for-outbreak/

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Sequence for Putting On and Removing Personal Protective Equipment (PPE)

                                   CLICK ON THE IMAGES BELOW - TO ENLARGE (2 page .PDF file)

      

      

http://www.cdc.gov/vhf/ebola/pdf/ppe-poster.pdf

http://www.cdc.gov/vhf/ebola/resources/factsheets.html

 

     

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Why I'll risk my life for Ebola patients

Hundreds of foreign aid workers are in West Africa treating people with Ebola. One of them is Cokie van der Velde who has just flown from the UK to Liberia. She explains why she has left the safety of her home to face the deadly virus.

I was first in Liberia five weeks ago and I believe the situation is now much worse. Back then, our treatment centres had already run out of room and we were starting to put people in corridors.

In the centre, people groan and cry out - the smell of blood, diarrhoea and vomit is awful - unfortunately there is also a very pervading smell of dead bodies.

I can only leave it to your imagination to understand what a pile of bodies smells like after a week in very hot, moist surroundings - it makes you feel sick quite a lot of the time.

http://www.bbc.com/news/magazine-29245149

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NHS staff are being asked to volunteer to fight Ebola outbreak

 A World Health Organization worker trains nurses to use Ebola protective gear in Freetown, Sierra Leone, where the spread of Ebola is accelerating Photo: Michael Duff/APBy Rebecca Smith - 22 Sep 2014 - telegraph.co.uk

Medical leaders have appealed for NHS doctors, nurses and paramedics to volunteer to treat Ebola victims in Sierra Leone.

A letter signed by the four most senior NHS medical officers directly asks for volunteers to staff a new hospital.

British military experts working alongside charities are setting up a 12-bed unit to treat infected healthcare workers and an additional 50 bed unit for ordinary citizens infected with the deadly virus.

http://www.telegraph.co.uk/news/worldnews/ebola/11110090/NHS-staff-are-being-asked-to-volunteer-to-fight-Ebola-outbreak.html

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How a Winnipeg lab became an Ebola research powerhouse

Researchers with the National Microbiology Laboratory in Winnipeg say they are optimistic that a tool to combat the Ebola virus may be on the horizon. (John Woods/Canadian Press) By Helen Branswell - The Canadian Press - Sep 21, 2014

Winnipeg is half a world away from the countries in Africa where Ebola, and its viral cousin, Marburg, occasionally slip out of their animal reservoir to start infecting and killing people, as Ebola is now doing in West Africa.

The current outbreak has infected at least 5,335 people and killed at least 2,622. To date, there has never been a case of either viral hemorrhagic fever infections within Canadian borders.

So why then is Canada's national lab an Ebola research powerhouse? Why is a facility on the edge of the Prairies, near North America's longitudinal centre, the site from whence some of the most promising Ebola research emanates?

http://www.cbc.ca/news/canada/manitoba/how-a-winnipeg-lab-became-an-ebola-research-powerhouse-1.2773397

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MSF chief: World losing battle with Ebola now

 

rt.com - Sep 22, 2014

While the world is preoccupied with Islamic State or political games around Ukraine, there’s another threat emerging from the West Africa - where people are dying by hundreds, reaped by the deadliest Ebola epidemic to be ever known to mankind. Efforts to contain it end in a failure, and the vaccine is nonexistent yet. Are we seeing another pandemic slowly growing up to strike at mankind? What should be done to stop it? What does it mean to be a doctor in a place where death reigns? We try to find out this together with the head of the Médecins Sans Frontières - Doctors Without Borders. Dr. Joanne Liu is on Sophie&Co today.

http://rt.com/shows/sophieco/189516-west-africa-ebola-threat/

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Why Raising Money To Fight Ebola Is Hard

  Medical workers in Monrovia, Liberia, put on their protective suits before treating Ebola patients Dominique Faget/AFP/Getty ImagesBy Zoe Chace - Sep 22, 2014 - npr.org

The response to the 2010 earthquake in Haiti was massive: Billions of dollars in donations poured in.

"It had everything," says Joel Charny, who works with InterAction, a group that coordinates disaster relief. "It had this element of being an act of God in one of the poorest countries on the planet that's very close to the United States. ... And the global public just mobilized tremendously."

People haven't responded to the Ebola outbreak in the same way; it just hasn't led to that kind of philanthropic response.

From the point of view of philanthropy, the Ebola outbreak is the opposite of the Haiti earthquake. It's far from the U.S. It's hard to understand. The outbreak emerged over a period of months — not in one dramatic moment — and it wasn't initially clear how bad it was.

http://www.npr.org/blogs/money/2014/09/22/349962559/why-raising-money-to-fight-ebola-is-hard

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